Chorea disease progress
As the disease progresses and a person’s ability to tend to his own needs reduces, carefully managed multidisciplinary caregiving becomes increasingly necessary. Tetrabenazine was approved in 2008 for treatment of chorea in Huntington’s disease in the US. Other drugs that help to reduce chorea include neuroleptics and benzodiazepines. Compounds such as amantadine or remacemide are still under investigation but have shown preliminary positive results.
Several symptoms are similar to those seen in Parkinson’s disease, and they differ from the chorea seen in individuals who develop the disease as adults. These young individuals are said to have “akinetic-rigid” HD or the Westphal variant of HD. People with juvenile HD may also have seizures and mental disabilities.